PRODUCTION OF CXC AND CC CHEMOKINES BY HUMAN ANTIGEN-PRESENTING CELLS IN RESPONSE TO LASSA VIRUS OR CLOSELY RELATED IMMUNOGENIC VIRUSES, AND IN CYNOMOLGUS MONKEYS WITH LASSA FEVER.

Production of CXC and CC chemokines by human antigen-presenting cells in response to Lassa virus or closely related immunogenic viruses, and in cynomolgus monkeys with lassa fever.

The pathogenesis of Lassa fever (LF), a hemorrhagic fever endemic to West Africa, remains unclear.We previously compared Lassa virus Plasma Torches (LASV) with its genetically close, but nonpathogenic homolog Mopeia virus (MOPV) and demonstrated that the strong activation of antigen-presenting cells (APC), including type I IFN production, observed

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GDP vs. GNH. A NEW PARADIGM

Human being should be seen as the most important asset of economic life, and its well-being should be considered as an important indicator in having a realistic account regarding the level of prosperity and evolution of a nation.Although the concept of Liquid Foundation GNH (Gross National Happiness) has been introduced by economists like Richard L

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Blocking connexin 43 and its promotion of ATP release from renal tubular epithelial cells ameliorates renal fibrosis

Abstract Whether metabolites derived from injured renal tubular epithelial cells (TECs) participate in renal fibrosis is poorly explored.After TEC injury, various metabolites are released and among the most potent is adenosine triphosphate (ATP), which is released via ATP-permeable channels.In these hemichannels, connexin 43 (Cx43) is the most comm

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